Justin Siefker

Office: Roberts Building, 303A, UCL

Email: justin.siefker.12@ucl.ac.uk

Education:

  • PhD, Chemical Engineering, University College London, London UK (2013-present)
  • MS, Chemical Engineering, Rensselaer Polytechnic Institute, Troy NY, USA (2012)
  • BS, Chemical Engineering, Rensselaer Polytechnic Institute, Troy NY, USA (2009)
  • BS, Psychology, Rensselaer Polytechnic Institute, Troy NY, USA (2009)

Research:

Over the last three decades there has been enormous growth in the field of biotechnology. This growth has created a wealth of knowledge ranging from the development of life saving protein therapeutics to the creation of synthetic alternative biofuels. Armed with this versatile knowledge base, the unique opportunity to incorporate biotechnology with other disciplines and fields emerges.  The integration of biotechnology with nanotechnology offers great potential for further understanding and diverse application.

Justin’s projects focus on the experimental and theoretical characterization of the fundamental behavior of proteins in mesoporous environments.  The goal of these projects is to develop bio-nanomaterial therapeutics and create immobilized bio-catalysts that have improved stability and enhanced activity. Understanding of adsorption, surface curvature, support surface effects (e.g., surface functionalization), protein-surface interactions, protein conformational structure, and protein transport in pores are all key to this goal. The results of this research have applications in bio-therapeutics, catalysis, bio-separations, and sensing.

Project: Nature-inspired enhancement of enzyme performance by confinement in nanopores

Publications:

  1. J. Siefker, P. Karande, and M.-O Coppens,
    "Packaging biological cargoes in mesoporous materials: opportunities for drug delivery"
    ,
    Exp. Opin. Drug Deliv.
    , 2014, 11, 1781.
    [Link]
Justin Siefker